Key Metrics

Mechanism of Action & Benefits

• An obligate anaerobic spore-forming bacterium that produces butyrate—a key short-chain fatty acid (SCFA) and the primary energy source for intestinal epithelial cells—promoting villus development and repair
• Strengthens intestinal barrier integrity by upregulating tight-junction proteins (ZO-1, claudin-1, occludin) and stimulating mucin secretion, reducing pathogen translocation across the gut wall
• Competes with pathogens for intestinal attachment sites and lowers luminal pH through SCFA production, inhibiting E. coli, Salmonella, and Clostridium perfringens
• Modulates host immune function by increasing secretory IgA and anti-inflammatory cytokines while suppressing pro-inflammatory signaling pathways
• Shifts the gut microbiota toward beneficial genera such as Lactobacillus and Bifidobacterium, supporting overall microbiota diversity and balance
• Demonstrated as a probiotic for poultry, swine, and aquaculture species, improving growth performance, gut health, and resistance to enteric disease
• Forms resistant spores that withstand gastrointestinal transit and feed processing, despite its vegetative cells being strict anaerobes

Recommended Dosage

Recommended minimum inclusion: 0.1–2×10⁸ CFU per kg body weight, adjusted by target species. For feed inclusion, calculate from body weight and target intake.